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DTR’s news round-up 2019: the stories that defined the year
Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.
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Inflammatory bowel disease (IBD)
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New study could lead to better treatments for autoimmune diseases
A study has found a new molecular process in mice that causes autoimmune diseases and has opened avenues for developing more effective autoimmune therapies.
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T cells could work as therapy for IBD in children, finds study
Researchers have found that a type of T cell, called a Tr1 cell, could work as a therapeutic strategy for inflammatory bowel disease in children.
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Detecting epigenetic signature may help people stay ahead of IBD
Researchers have reported finding on an epigenetic signature in patient cells that appears to predict inflammation risk in Crohn's disease...
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Gene manipulation holds the key to personalised medicine
Researchers propose a novel approach to manipulate genes that may hold the key to the future of personalised medicine...
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Stem cell-derived intestine model mimics innate immune responses
A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses.
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Researchers produce the first draft cell atlas of the small intestine
By surveying gene expression, researchers have created a reference atlas for understanding the biology of inflammatory bowel disease and food allergies, among other conditions...
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CRISPR gives new insight into autoimmune disorders
Researchers have used a modified version of the gene-editing technique CRISPR in search for gene activators...
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Mironid secures £4.3 million in Series A funding
20 June 2016 | By Victoria White, Digital Content Producer
The funding, led by Epidarex Capital, will support the Mironid’s internal research and preclinical development programmes...
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Researchers identify interactions between immune system pathways
17 June 2016 | By Victoria White, Digital Content Producer
Researchers have identified interactions between immune system pathways which could improve the treatment of diseases such as inflammatory bowel disease...
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Enterome signs IBD therapy agreement with Vertex
19 April 2016 | By Victoria White, Digital Content Producer
Enterome has signed a license agreement with Vertex to research, develop and commercialise novel small molecule FimH antagonists...
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Galapagos licenses HUB Organoid Technology for use in cystic fibrosis and IBD research
15 July 2015 | By Victoria White
Galapagos has entered into a licensing agreement with the HUB foundation for use of Organoid Technology for preclinical research in cystic fibrosis and IBD...
