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Disrupting the mechanism that EGFR-driven lung adenocarcinoma uses to alter macrophages’ lipid metabolism could inspire new treatments.
New Salk Institute, US, research could lead to the development of new HIV therapeutics that overcome resistance to existing drugs.
US researchers administered a therapy to Alzheimer’s patient-derived neurons in the lab, eliminating deteriorating cells, leading to positive consequences for the remaining healthy cells.
The molecules, called SGDGs, may lead to new ways to treat age-related neurological diseases.
New research by the Salk Institute has shown cellular rejuvenation therapy safely reverses signs of ageing in mice.
A drug called CMS121 given to mice with Alzheimer's-like disease treated their memory loss, allowing them to perform the same as healthy control mice in tests.
Researchers have demonstrated that cysteinase, a new drug compound, can starve pancreatic cells of cysteine supply, causing ferroptosis.
A new study has shown in three dimensions how drugs bind to HIV, which could be used to improve the design of drugs or develop novel therapies.
Researchers have discovered a microprotein that acts as a regulator of cell stress, which could be used in developing therapies for a wide range of conditions.
Mouse blastocyst-like structures called blastoids have been developed by a team which could be used to study early developmental diseases.
Salk scientists discover a pair of enzymes that drive non-small-cell lung cancer by promoting inflammation which could inform the development of new therapies.
A study has found that using skin cells and transforming them into neurons is a valid approach to study neurodegenerative diseases such as Parkinson's...
Researchers in California have developed a method to facilitate control of nuclear pore numbers in cells. The capability is expected to glean valuable information to aid cancer treatment.