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Uncovering the functional role of sRNAs in bacterial adaptation
Researchers find how antibiotic treatments influence the microbiota, providing new strategies for preventing antibiotic-induced damage.
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California University
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The implications of EN-1 overexpression in late-stage PDAC
Using tumour organoids, researchers identified that overexpression of Engrailed-1 blocked genes associated with natural cell death.
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Newly identified cell type uncovered in the thymus
Microfold cells (M cells) are primarily known for their role in the intestinal epithelium. However, the researchers discovered similar cells in the thymus.
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Five recent cell and gene therapy discoveries
This article highlights five of the latest findings using cell and gene therapy techniques that could be used in the development or design of new therapies.
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New machine learning model could encode words to kill cancer cells
US researchers, using new machine learning techniques have developed a virtual molecular library of “words” that encode commands to kill cancer cells.
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First use of CRISPR to substitute genes for cancer treatment
US scientists, using CRISPR technology, removed specific genes in humans to allow the immune system to be more activated against cancer.
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Is the Nile rat the new animal model for diabetes research?
US researchers, using genome sequencing, put forward the Nile rat as the new model organism for diabetes research.
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Pre-clinical model of appendiceal cancer developed
Researchers from the University of California have developed the first pre-clinical model of appendiceal cancer, containing all elements of the tumour.
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Newly discovered GPCR signalling process opens possibility for novel therapies
US researchers have found that G protein-coupled receptors function in a way not previously known, which suggests untapped potential.
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First full sequence of a human genome completed
After two decades, researchers have generated the first complete, gapless sequence of a human genome
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Findings reveal possible connection to substance use disorders and metabolic dysfunctions
A new study on substance abuse disorders highlights an existing connection between specific neurons and peripheral organs.
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Milestone reached in search of vaccine against respiratory syncytial virus
A new study has showed how a bioengineered RSV protein vaccine can induce a protective immune response in animal models.
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European patent upheld for foundational CRISPR-Cas9 intellectual property
Arguments filed in opposition to a patent for foundation CRISPR-Cas9 intellectual property have been broadly rejected by the European Patents Office.
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Antiviral treatments lead to development of a new kind of cancer drug
Drugs that were being developed to treat enterovirus have also been found to treat certain cancers in mice.
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Mutant form of Ebola could be used in vaccine development
A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.