news
Blocking IL-17 could provide new multiple sclerosis treatment strategy
Researchers have revealed that inhibiting IL-17 could prevent the effects of autoimmune diseases, including multiple sclerosis.
List view / Grid view
Disease Research
news
Interaction site for serotonin type 3A and RIC-3 chaperone identified
To address the receptor dysfunction associated with several neurological diseases, scientists have provided novel insights into a protein-protein interaction that could lead to more effective treatments.
news
Kidney stem cells isolated from urine could be the future of regenerative therapies
Research into alternative stem cell sources has identified urine derived renal progenitor cells (UdRPCs) as a possible option for use in regenerative kidney therapies in the future.
news
C1 compound identified as promising Alzheimer’s drug candidate
Researchers have screened thousands of drugs to discover that C1 effectively blocks the production of amyloid fibrils, so could be an effective therapeutic.
news
Method to make integrin receptor-targeting drugs safer in future presented in study
Research into the structure of the drug-integrin complex has enabled the creation of drugs which inhibit integrin as effectively as currently used compounds, without causing excessive bleeding.
news
Influenza B M2 proton channel structure resolved by researchers
Research into the M2 proton channel of influenza B has revealed its structure, which the team hope can aid in the development of targeted therapeutics to block the channel and treat the condition.
news
RNA methylation knock-out mutant could be potential HMPV vaccine
Research has shown that human metapneumovirus uses RNA methylation to hide from the immune system and that knocking out this methylation creates a mutant strain which acts like a vaccine.
news
Molecule of blood found to be effective against lupus
Scientists have found that a molecule present in our blood, called C4BP (β-), could be used in a therapeutic capacity for lupus as well as potentially other autoimmune disorders.
news
Precise features of CAR T cell-resistant cancer have been identified
The mechanism that prevents destruction of cancer cells by CAR T-cell therapy has been identified by researchers in Pennsylvania.
news
Machine learning could improve tissue model purity
An innovation using artificial intelligence to analyse developing lung cell developments in vitro revealed what promotes them to develop and allowed researchers to create better quality lung tissue models.
news
Macrophages could be the target of novel heart attack therapies
Research determined macrophages’ role in forming a permanent cardiac scar after a heart attack, the researchers suggest altering this behaviour may make the scar temporary and allow restoration of heart function.
news
Researchers suggest IMPDH enzyme could be used to target sleeping sickness
Research into drug targets for sleeping sickness parasite T. brucei has characterised the inosine-5'-monophosphate dehydrogenase (IMPDH) enzyme, providing a possible novel avenue for therapies.
news
Putrescine could be a therapy for chronic inflammatory diseases
Research has identified that putrescine, which aids macrophages in clearing dead cells, is lacking in atherosclerosis animal models and could be a potential therapeutic for the condition.
news
Autophagy: the key to effective MERS-coronavirus treatment?
A promising route for tackling the often-fatal MERS-coronavirus (MERS-CoV) has been identified by researchers in Germany.
article
Body-on-chip technology: resolving current limitations in drug discovery
Researchers have developed a new body-on-chip technology that can demonstrate the pharmacokinetics and pharmacodynamics of drugs in a pre-clinical setting without the need for animal testing.
