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Drug Discovery

 

In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.

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A high-throughput macrodomain assay to identify coronavirus drugs

22 September 2022 | By ,

In the search for a rapid, easy way to identify drugs to fight SARS-CoV-2, researchers from across the US came together to develop and apply a high-throughput ADP-ribosylhydrolase assay, ADPr-Glo. Here, Dr Veronica Busa and Dr Anthony Leung from Johns Hopkins University describe the ADPr-Glo assay and how it can be…

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Drug Target Review – Issue 3 2022

14 September 2022 | By

In this issue are articles on synthetically engineered bacteria to deliver therapeutics, how single-molecule fluorescence resonance energy transfer was used to image GPCRs and a new assay to identify coronavirus drugs. Also included are pieces on vaccine development, monoclonal antibodies and neuroscience.