Extensive tumour protein analysis reveals new therapy targets
New research has categorised hundreds of cancers based on their common protein mutations, highlighting cell components and tumour microenvironments as possible new therapy targets.
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Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
New research has categorised hundreds of cancers based on their common protein mutations, highlighting cell components and tumour microenvironments as possible new therapy targets.
A new study has presented a potential strategy for a universal human cancer vaccine. This article delves into the researchers’ findings, exploring their methodologies and results.
VTP50469, a new targeted therapy for MLL-rearranged leukaemia, shows greater efficacy and fewer side-effects in mice, according to new research.
This article highlights some of the most recent drug target discoveries that could be used to develop and design a treatment for pancreatic cancer.
Researchers have developed a cell line that allows the mechanisms of prostate cancer bone metastasis to be studied in immunocompetent mice.
The earliest genetic root of Wilms' tumour has been discovered, which could not only lead to improved treatments but to one day being able to screen for cancers like this before tumours develop.
Researchers have reprogrammed CAR T cells to prevent them becoming exhausted after prolonged activity, presenting a possible new therapy for solid tumours.
A new mechanism has been reported for detecting foreign material during early immune responses which may help detect elusive cancers.
Researchers have found that the TRAP-alpha insulin biosynthesis pathway is essential in both cancer and diabetes, with a common primordial ancestor discovered in C. elegans.
The new screening technique may enable development of novel combination-immunotherapy regimens against cancers and persistent infections.
A study conducted on human pancreatic tumours transplanted in mice reveals promise for an effective therapy in the future, say researchers.
A study has demonstrated how mutations in early colon cancer prevail and grow into malignancies, using fluorescent imaging.
A new study into the molecular causes of acute lymphoblastic leukaemia could lead to a new target for therapy.
A new discovery that healthy liver tissue surrounding a tumour activates a defence mechanism that restrains tumour growth could inspire new therapeutic approaches that mobilise normal cells to kill cancer cells.
A new signalling pathway has been identified that may help further the understanding of blood clot formation in cancer patients and presents a new drug target for reducing cancer-associated complications.