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Issue #2 2017

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Inflammatory biomarkers as a herbal anti-arthritic drug discovery tool

11 July 2017 | By , , , , ,

Rheumatoid arthritis (RA) is joint-related, immune-based inflammatory disarray that affects almost 1% of the world’s population. The most evidenced pathogenesis is T-cell activation, which leads to clusters of differentiation (CD) in the T-cells and concurrently increases various inflammatory biomarkers.

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Development by design methodology: the key to successful manufacturing of patient-specific cell therapies

11 July 2017 | By ,

Recognised as the next wave of medicine, cell therapies have made significant strides over the last several years. But such advancements can present unique challenges, especially as more products move out of the clinic and toward commercialisation. And unlike typical pharmaceuticals, cell therapies rely heavily on the manufacturing process to…

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Targets In-Depth Focus 2017

5 June 2017 | By

Included in this Targets In-Depth Focus: Intracellular target validation in cellular systems; New drug targets identified to defend against chlamydia infections using CRISPR and stem cells; Novel solutions for tough targets with real bite...

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Screening In-Depth Focus 2017

5 June 2017 | By

Included in this Screening In-Depth Focus: Phenotypic and target-based screening; Killing cancer cells using clinical drug resistance; Inflammatory biomarkers as a herbal anti-arthritic drug discovery tool...