Gene therapy for epilepsy shows promise in animal models
An AAV-delivered gene therapy has demonstrated success in animal models of temporal lobe epilepsy, so could be a therapeutic option for human patients.
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Specific gene implicated in cardiovascular calcification
Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
Potential new target identified for the treatment of gout
A new therapeutic target for gout has been identified which could lead to new treatment strategies that could improve the quality of life for patients who suffer from the condition.
Function of protein involved in liver cancer discovered
The involvement of clathrin in the development of liver cancer has been described for the first time, which could lead to more targeted therapy.
First detailed 3D image of astrocytes produced by researchers
Researchers have compiled images to create the first detailed 3D models of astrocytes, which could be used in the development of therapeutics to aid their function.
Clues discovered for why MYH9 gene mutations cause human disorders
A new study has demonstrated for the first time that mutations that affect myosin motor activity result in slower cell movements in vivo.
Inflammatory protein can protect against the spread of herpes virus
A new study that examined the protein IL-36γ could aid in the development of novel therapeutics to protect against STIs.
Protein vital for T cell formation and function revealed
Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.
Intervening tau accumulation could halt progression of Alzheimer’s
A group of researchers has found that tau misfolding is not harmful in itself, but instead the cellular processes its affects kills neurons.
Genetic mutation in monkeys identified as cause of Bardet-Biedl Syndrome
A study has revealed that in rhesus monkeys, a genetic mutation could be the cause of Bardet-Biedl Syndrome, providing a way to study the disease and develop therapies.
Researchers reveal how body repairs damaged DNA
A team has imaged the process that the body uses to stabilise DNA, which could be used to develop therapies for conditions such as cancer.
Protective antibody discovery could lead to better flu treatments
Researchers have identified a set of three antibodies that they suggest could become the basis for a new antiviral treatment and inform the development of new influenza vaccines.
Rhomboid protease role observed using dynamic imaging
Researchers have been able to watch rhomboid proteases in a native lipid environment which may be useful for the development of Parkinson's and malaria medication.
Microprotein revealed to regulate cell stress by study
Researchers have discovered a microprotein that acts as a regulator of cell stress, which could be used in developing therapies for a wide range of conditions.
New antiviral drug demonstrated to effectively treat influenza in models
A new antiviral drug has been reported in a study that researchers believe has high clinical potential as a next-generation influenza drug.
