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Novel antibiotic compound revealed through artificial intelligence screening
A new antibiotic compound has been identified by researchers who designed a machine-learning algorithm to screen millions of molecules.
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Genome screen in mice reveals Huntington’s disease gene target
Researchers have conducted a genetic screen in mice to discover a family of genes that contributes to the development of Huntington's.
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DTR’s news round-up 2019: the stories that defined the year
Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.
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Mucus has been shown to tame microbes in new study
Glycans, which are found in mucus, have the ability to regulate how microbes behave and could lead to new therapeutics.
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Automation of complex synthetic biological molecules enabled by robotics
A new platform combines AI, flow chemistry and robotics to minimise the need for human intervention in the synthesis process.
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Blood-brain barrier role in Alzheimer’s patients revealed by tissue model
A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.
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Vaccine strategy devised to boost T-cell therapy
A research team has developed a vaccine that advances anti-tumour T-cell populations and allows the cells to invade solid tumours.
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Gut microbiome identified as cause of IBD, study finds
A study has detailed the change in the gut microbiome, increasing the potential for new IBD therapies.
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Magnetic microbots could help drug-delivery nanoparticles reach their targets
MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumour or another disease site.
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MRI sensor to image activity deep inside the brain
A method of imaging calcium activity that is based on magnetic resonance imaging (MRI) could help to image deep within the brain...
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Ingestible capsule controlled wirelessly could treat diseases
Researchers have designed a drug delivery capsule that can stay in the stomach for up to 1 month, and could sense and treat infections...
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Repurposing wasp venom as antibiotic drugs
Researchers have used wasp venom to create variants of a peptide that is potent against bacteria but nontoxic to human cells...
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Ageing hallmark in neurons discovered by biologists
Oxidative stress occuring in neurons produces unusual piles of short snippets of RNA and could be a marker of neurodegenerative diseases...
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Profiling the genome hundreds of variations at a time
A CRISPR-Cas9 high-throughput strategy creates the possibility to rapidly profile and identify genes and DNA sequence variations key to different traits and diseases.
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Organ-on-chip technology tests for hepatitis B virus
Scientists have become the first in the world to test how pathogens interact with artificial human organs...