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New tool reveals DNA structures that influence disease
Researchers have created an algorithm that locates and analyses DNA structures which are linked to the development of certain diseases.
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Macrophage response mechanism to pathogens revealed
A study has found the processes used by macrophages in their immune response, which could be used in the development of new vaccines.
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Multi-omics approach yields novel insight for peanut allergies
Researchers in New York have identified novel genes associated with the severity of peanut allergies and noted how these genes interact with other genes during allergic reactions. The findings could lead to better treatments for peanut allergies.
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Antibodies could be used as nanotechnology builders
Endogenous human antibodies can be used to build and dismantle 2D and 3D DNA nanostructures, finds new research.
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How will CRISPR evolve in the future?
CRISPR is a tool used by researchers to precisely edit genes and has shown potential for treating genetic diseases. This article delves into some recent developments and explores what the future holds for CRISPR.
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Mucin 6 gene indicates predisposition to late-onset Alzheimer’s
Scientists have idenified that variation in a gene called Mucin 6 appears to indicate a tendency for acquiring Alzheimer’s disease.
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Application note: Automated Extraction of High Molecular Weight DNA
SmartExtraction significantly simplifies the entire automated workflow of DNA extraction.
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Enzyme involved in cancer growth imaged for first time
A study has revealed the structure of an enzyme that promotes cancer growth by mutating RNA, which could be used in the development of cancer treatments.
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MaveDB: database to aid research into genetic causes of disease
Researchers in Australia and the US have launched the first open-source database detailing genetic variants that impact human health and disease.
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Histones revealed by study as critical for cell identity
Researchers have shown that histones are vital in silencing genes and that their position is inherited in new cells, providing insight into how cancer cells can become resistant to therapy.
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Specific gene implicated in cardiovascular calcification
Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
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Protein vital for T cell formation and function revealed
Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.
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Researchers reveal how body repairs damaged DNA
A team has imaged the process that the body uses to stabilise DNA, which could be used to develop therapies for conditions such as cancer.
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New gene editing tool could correct 89 percent of genetic defects
'Prime editing', a new CRISPR genome-editing approach, is capable of directly editing human cells in an accurate and efficient way.
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Researchers create blastocyst-like models from mouse cells
Mouse blastocyst-like structures called blastoids have been developed by a team which could be used to study early developmental diseases.
