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Hit-to-Lead

whitepaper

ebook: The definitive guide to understanding protein stability

16 June 2020 | By NanoTemper Technologies

Learn how to measure protein stability, why it’s important, and what the key technologies are available to measure it.

webinar

Improving cell-based assays and their future in drug discovery

15 June 2020 | By Horizon Discovery

Watch our on-demand webinar with Horizon Discovery which summarises the challenges in translating promising pre-clinical therapeutic candidates into clinical success.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

whitepaper

ebook: How FBDD improves hit rates & delivers high-value targets

8 June 2020 | By NanoTemper Technologies

Learn how fragment-based drug discovery improves hit rates and delivers higher-value targets using various biophysical methods.

whitepaper

Guide: Five ways biophysical tools help brain studies

3 June 2020 | By NanoTemper Technologies

Learn why researchers turned to biophysical methods to expose the molecular mechanisms of neurodegenerative diseases.

whitepaper

ebook: How to start your own lab

26 May 2020 | By NanoTemper Technologies

Learn practical tips from eight Principal Investigators about how to start your own lab.

whitepaper

ebook: High-content analysis and infectious disease

12 May 2020 | By PerkinElmer

Learn how you could use high-content analysis for functional & phenotypic assays in your infectious disease research or drug discovery.

webinar

Establishing Alpha CETSA HT in primary screening

7 May 2020 | By PerkinElmer

High-throughput screening (HTS) cascades have evolved to ensure that high quality hits can be identified from large screening collections.

news

Three new assays to test COVID-19 antivirals developed

30 April 2020 | By Victoria Rees (Drug Target Review)

A series of three new assays to screen for drug compounds or proteins that combat the COVID-19 coronavirus has been developed.

news

Researchers identify lead compounds for treatment of telomere diseases

23 April 2020 | By Victoria Rees (Drug Target Review)

Researchers investigating telomere dieases such as dyskeratosis congenita have found lead compounds that reverse cellular ageing in mouse models of the condition.

news

Lead SARS-CoV-2 inhibitor compound identified by researchers to treat COVID-19

23 April 2020 | By Victoria Rees (Drug Target Review)

Researchers have found a lead compound which they say inhibits SARS-CoV-2 viral replication and demonstrates good pharmacokinetic activity in vivo.

tablets, capsules and a laboratory scientist in a white coat on a swirling blue background

news

Screening 10,000 compounds identifies six potential COVID-19 therapeutics

17 April 2020 | By Hannah Balfour (Drug Target Review)

High-throughput screening of thousands of compounds has revealed several candidates, including lead compound ebselen, with the potential for treating COVID-19.

news

Celltrion selects 14 lead monoclonal antibodies for COVID-19 treatment

16 April 2020 | By Victoria Rees (Drug Target Review)

After screening 300 antibodies, Celltrion has identified the 14 most powerful that could potentially combat the COVID-19 coronavirus.

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