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Proteomic approach reveals metastatic melanoma resistance to therapies
A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
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Immunotherapy
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Immune cell function in cancer immunotherapy revealed
Researchers have discovered the roles that immune cells play in tumour growth and breast cancer immunotherapy which could aid in drug development.
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T-cell subset association with type 1 diabetes demonstrated by study
A new study from the University of Eastern Finland has shown that peripheral T helper cells may have a role in the development of type 1 diabetes.
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Industry objects to unproven T-cell preservation services
The ISCT is objecting linking the benefits of cellular immunotherapy with third party offerings of T-cell banking for future therapeutics.
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Novel nano-vaccine for melanoma developed
A novel nano-vaccine has been developed which has proven effective in treating primary tumours and metastases that result from melanoma.
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New evidence shows cytotoxic T cells can destroy targets of large mass
New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
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Scientists have discovered important redundancies in T cells
Redundancies have been discovered in the biochemical signalling pathways of immune cells which could impact cancer immunotherapy.
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Stem-cell technologies in immunotherapy
This article outlines the exciting developments that are taking place with immunotherapies and demonstrates how stem-cell technologies are proliferating the paradigm shift in how we tackle cancer treatment.
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Immune cells could be key to tuberculosis treatment, study finds
Researchers have found that certain immune cells aid in fighting tuberculosis bacteria, providing a new drug target.
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Stem Cell In-Depth Focus 2019
This in-depth focus looks at the modification of stem cells to facilitate their efficient delivery to tumours, highlighting the new development of pluripotent stem cells.
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Update on the development of new novel cancer immunotherapy
The SCIB2 vaccine is to to be administered using new nanoparticle formulation in planned Phase 1/2 clinical trial.
webinar
A high-throughput approach to developing T-cell immunotherapies
23 May 2019 | By Sartorius
Join us as we discuss the promises and pitfalls associated with developing individualised antigen-specific T-cell therapy products for clinical use.
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Artificial chemical receptor developed to assist in T cell engineering
Engineered T cell immunotherapy (such as chimeric antigen receptor T cell (CAR-T) and T cell receptor T cell (TCR-T) therapy), could potentially be used as a therapeutic strategy for tumour treatment.
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Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumours
Researchers have used single-cell sequencing to map the landscape of myeloid cells in tumours from patients with lung cancer...
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Counteracting T-cell exhaustion in CAR-T cancer therapies
Engineered T-cells that target NFAT and Nr4a proteins could help to prevent the exhaustion of T-cells during CAR-T immunotherapy...
