T cell homing beacons for lungs identified by researchers
Molecules that are critical for T cells to travel to and populate the lungs have been identified which could strengthen vaccines against influenza.
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High-throughput screening used to discover new class of antibiotics
Researchers have used a high-throughput screening method to test over 125,000 molecules and identify a new class of antibiotics.
Neuronal link between chronic pain and depression discovered
The mechanism in the brain connecting chronic pain and depression could lead to treatments for both, according to researchers.
Scientists discover unique imaging technique to view synapse proteins
Researchers in the US have devised a new way to clearly image proteins located in synapses, which they hope will faciliate future treatment for diseases associated with blocked gene expression.
Researchers find DNA therapy could treat patients with DMD
A study has revealed that using DNA-like molecules to repair gene mutations in models could act as a successful therapy for patients.
Novel CAR T-cell therapy for leukaemia and lymphoma
Scientists in the US have developed a promising new CAR T-cell therapy that targets the BAFF-R protein, which has demonstrated superior cancer destruction to existing FDA-approved CAR-T therapies.
Researchers identify bacteria defence system mechanism
The process that bacteria use to defend themselves has been revealed by researchers, who also demonstrated how to activate the process.
Possible target found for idiopathic pulmonary fibrosis treatment
A new study shows that using therapeutic antibodies to block the interleukin-11 protein can reverse idiopathic pulmonary fibrosis.
Key protein in chikungunya virus replication identified
Researchers have found that the FHL1 protein plays a key role in chikungunya virus replication and pathogenesis.
High-throughput method used to identify cancer drug candidates
A study using high-throughput screening has revealed some promising compounds that could be used in future cancer treatments.
Mechanism behind glioblastoma survival revealed by study
Researchers have discovered the process that enables glioblastomas to avoid the effects of the immune system, presenting an immuno-oncology target.
Method to reactivate ‘tumour suppressor’ genes discovered
A new method to reactivate 'tumour suppressor' genes switched off by cancer cells could lead to new targeted biotherapies for cancer.
Device using small biomagnets could result in faster drug discovery
A new platform brings together genome editing with magnetic cell sorting to reveal new drug targets for cancer and regenerative medicine.
Researchers reveal how fungi produce potential therapeutic compounds
A team has discovered that fungi use the Diels-Alder reaction to assemble new compounds that have potential pharmaceutical uses.
New study shows insight into how cells maintain their identity
A new study shows the ways in which epigenetic mechanisms control the activity of genes and may have an impact on the future treatment of certain cancers.
