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Drug discovery for COPD treatments
In this article, Drug Target Review’s Ria Kakkad shares some of the most recent progress in discovering a drug for COPD, a disease that remains a major challenge in the medical industry.
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Pathology & Molecular Medicine
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Research highlights interaction of mycobacteria with red blood cells and its role in lung disease
A new study has found that mycobacteria are associated with red blood cells at lung infection sites, an interaction that has escaped scientists for 140 years.
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New Oxford-GSK Institute aims to unravel complex diseases
GlaxoSmithKline (GSK) and the University of Oxford will collaborate to investigate diseases using technologies such as functional genomics and machine learning.
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Novel label-free exosome profiling method shows success at detecting cancer
A new label-free technique has been developed for molecularly specific exosome biosensing in diagnostics and biomarker detection.
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Immune cells found co-operating to capture and “eat” bacteria
Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.
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Imaging Mass Cytometry™ of malignant tissue architecture: rare single cells to structured multi-cellular communities
14 April 2021 | By Fluidigm
Watch our free on-demand webinar to learn more about using Imaging Mass Cytometry™ (IMC™) to measure over 40 protein targets with subcellular resolution.
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A novel approach to unravelling the mysteries of Alzheimer’s
The heterogenous and dynamic nature of protein aggregates makes them a particularly challenging class of structures to study. In this article, Professor Tuomas Knowles and Dr Sean Devenish present a novel approach to studying protein structures that could aid in understanding the complexities of Alzheimer’s disease and identify future therapeutic…
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New discovery shows ability of Schwann cells to generate myelin
Research from Oregon Health & Science University could lead to new therapies to heal nervous system disorders.
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Diverse Parkinson’s-related disorders may stem from different strains of same protein
Researchers found that the type of brain cell afflicted in Parkinson’s-related brain disorders dictates which pathological form of α-synuclein (α-syn) protein becomes the disease culprit.
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New weakness found in most common childhood malignant brain tumour
A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.
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New Alzheimer’s animal model more closely mimics human disease
Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.
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Expert view: Advances in NGS technology
The multiplex and high-throughput capabilities of next-generation sequencing (NGS) allow researchers to study an immense number of DNA/RNA molecules per run, bringing opportunities to study biological or clinical research questions that could not be addressed before...
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New research highlights key differences between mice and men
Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs that have worked in animal experiments are not equally successful in humans. The researchers discovered differences – as well as hitherto unknown similarities – in the function of insulin-producing beta cells.
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Human neurons in mouse brains are more susceptible to Alzheimer’s pathology
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
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Tackling the spread of pathogens in transport hubs
Ilpo Kulmala, Principal Scientist at VTT Ltd, explains the role that transportation plays in the spread of infectious diseases...