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Previous studies of human microbiome may be biased in favour of Global North
A new study has suggested that previous global research into the human microbiome is heavily biased in favour of wealthy countries such as the US and UK.
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Microbiology
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Tweaked bacteria genes activate heart cells in mice
Researchers have shown that engineered bacterial genes coding for sodium ion channels could lead to novel gene therapies for electrical heart diseases.
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Scientists discover mechanism that links autism and intestinal inflammation
The new research shows how interleukin-17a (IL-17a) can alter the trajectory of immune system development and cause gut inflammation.
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Machine learning models predict antibiotic resistance spread
Scientists have used several machine learning models to predict bacterial gene exchange, which could reveal novel antibiotic targets.
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New antibiotic a possible alternative to treat Lyme disease
The antimicrobial hygromycin A was shown to clear Lyme disease in mice, representing a promising therapeutic against the disease.
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Antibiotic-free hydrogel fights against drug-resistant bacteria
New dendritic hydrogels were tested against several infectious bacteria and could be used as an an antibiotic-free treatment in the future.
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New single-cell and metagenomic technique can characterise microbes
The metagenomic method, termed SMAGLinker, could improve the accuracy and resolution of microbial characterisation to improve medicine design.
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Ex vivo stem cell treatment a promising therapy against MRSA
A new ex vivo model treated animal wounds with mesenchymal stromal cells (MSCs) and reduced MRSA infection, expanding therapeutic options for humans.
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New Gut Cell Atlas reveals genetic origins of Crohn’s disease
The Gut Cell Atlas comprises 428,000 cells in the gut and sheds light on the origin of Crohn’s disease and other intestinal diseases.
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Detergent-like APOL3 protein shown to kill bacteria in human cells
Researchers have revealed that the protein APOL3 acts as a detergent in human cells, potentially leading to new antibacterial treatments.
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Scientists develop novel strategy for tuberculosis vaccine
A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.
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New study may improve enzyme replacement therapy for Pompe patients
Researchers have developed a new method that could make enzyme replacement therapy more efficient for Pompe disease treatment.
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New study discovers how Parkinson’s-linked protein attacks mitochondria
Researchers have used fruit fly larvae to explore how alpha-synuclein impacts the mitochondria, advancing the study of Parkinson’s disease.
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Researchers reveal how microbiome bacteria adapt through transmission
Scientists have used genetic sequencing to demonstrate how the transmission of gut bacteria influences its evolution and functions, which could effect human health.
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Artificial intelligence may reveal how microbiome affects vaccine response
Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.